PO-05-089 COMPARISON OF VIRTUAL HEART ARRHYTHMIA ABLATION TARGETING PREDICTIONS WITH AREAS OF ISOCHRONAL CROWDING IN SCAR-DEPENDENT VENTRICULAR TACHYCARDIA
نویسندگان
چکیده
Isochronal late activation mapping (ILAM) is a functional substrate technique which detects deceleration zones (DZ) in those with scar-dependent VT. DZ have been shown to correlate the critical isthmus during re-entrant Personalised virtual heart arrhythmia ablation targeting (VAAT) aims non-invasively identify optimum targets through computational modelling. The association of VAAT predictions unknown, nor effect extrastimulus pacing on identification DZ. To assess relationship between predicted areas slow conduction ILAM Gadolinium-enhanced MRI scans were used reconstruct models. Simulated ventricular was performed demonstrate VT inducibility and predict lesion sets terminate all likely VTs ILAMs generated by annotating latest electrograms right at 20ms above VERP. defined as > 3 isochrones 1cm radius. superimposed invasive ILAM. spatial assessed. identified RV compared. 11 patients (100% male) underwent protocol. 3195 ± 935 EAM points per patient analysed. Mean VAAT-predicted area 11.2 4.3 cm2 representing 22.3% total infarct area. 13 (mean 1.2 patient, range 0-3). 10/13 (76.9%) located within 5mm site, whereas 3/13 (23.1%) remote (>5mm from site). Extrastimulus 25 2.3 1-4). 21/25 (84%) 4/25 (16%) remote. More compared (25 vs 13, p = 0.04). mean distance pacing-identified extrastimulus-identified not significantly different (3.3 6.7 mm 2.9 5.4 respectively, 0.84). 11/13 (84.6%) also pacing. 14/25 (56%) novel, having detected Deceleration visualised are closely spatially associated for ablation. identifies more
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ژورنال
عنوان ژورنال: Heart Rhythm
سال: 2023
ISSN: ['1556-3871', '1547-5271']
DOI: https://doi.org/10.1016/j.hrthm.2023.03.1340